Caffeine FDA Link Generic

A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling.

Also Known As:

No Doz; Vivarin; 1,3,7-Trimethylxanthine; Caffedrine; Coffeinum N; Coffeinum Purrum; Dexitac; Durvitan; Percoffedrinol N; Percutaféine; Quick-Pep; Quick Pep; QuickPep; 1H-Purine-2,6-dione, 3,7-dihydro-1,3,7-trimethyl-

Pharmalogical Action Categories:

Central Nervous System Stimulants
Phosphodiesterase Inhibitors
Purinergic P1 Receptor Antagonists

Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Xanthines: 123
    - Caffeine: 7695
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Purinones: 2
        Xanthines: 123
        Caffeine: 7695

Steve J Holman Selected Research

Steve J Holman Research Topics

Disease

Drug/Important Bio-Agent (IBA)